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Defect in DNA damage response (DDR) is a common feature of cancer cells, which regulates tumor growth and Immune response.
Aim is to discuss about the involvement of DNA repair systems in cancer prevention and the classes of genotoxins that are commonly used for the treatment of cancer.
 

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Cancer is a genetic disease and the gene variations are the only factors that finally cause cancer. This session discuss about the genetic makeup of thousands of cancer samples, yielding new insights into the genes that drive the many and varied forms of the disease
 

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The term ‘Gynecological Cancers’ comes with the medical condition in which cancer or tumor cells develop in the reproductive organs of a woman’s body.
Gynecological cancers are one of the leading causes of cancer-related deaths in women worldwide. Lakhs of women are diagnosed with gynecological cancers and hence, it is important to be aware of the various types of gynecological cancers.
There are six types of gynecological cancers of which three are common and the other three are rare which are listed below.
Uterine cancer
Cervical cancer
Ovarian cancer
Vulvar cancer
Vaginal cancer
Gestational trophoblastic tumor
 

Best Cancer and oncology research conference 2025

Spectus Meetings in Barcelona, Spain

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Emerging single-cell multi-omics sequencing technologies allow the capture of multiple modalities from a cell, including its epigenome, transcriptome, epi-transcriptome and proteome. This integration combination of multiple layers of information also requires tailor-made computational tools for integrative analyses.

Multiomics sequencing methods are ideally placed for Cancer biology tumor - heterogeneity, cancer progression and its interactions with the microenvironment, mechanisms of response or resistance to therapy research.
 

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Through laboratory, clinical, and epidemiologic research, scientists have shown that the diseases of cancer occur not as single, catastrophic events, but rather as the result of a complex and long-evolving molecular process. The intervals between initiation of the cancer process and occurrence of the invasive disease vary by organ and tissue sites, and some may take decades.

Many opportunities exist to make greater progress in cancer prevention. Just as we are increasingly able to identify the best treatments for a person’s cancer based on the genetic abnormalities of their tumor, fully characterizing a person’s genetic makeup and understanding their environmental exposures over time will enable us to tailor personalized measures to screen for and prevent cancer.
 

Best Cancer and oncology research conference 2025

Spectus Meetings in Barcelona, Spain

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Cell signaling – also sometimes referred to as signal transduction or transmembrane signaling - controls basic cellular activities via complex responses. Signaling pathways coordinate communication between the cell surface and nucleus, between different cells, and between cells and the extracellular matrix.
 

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Next Generation Cancer Models session aims to provide the research community to discuss on rich resource of diverse, fully annotated next-gen models (NGCMs) to better study disease biology.
 

Best Cancer and oncology research conference 2025

Spectus Meetings in Barcelona, Spain

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Radiation oncology (radiotherapy/radiation therapy) is a medical specialty that is an essential part of a multidisciplinary approach to cancer treatment by utilizing high-energy beams such as X-rays or protons. The goal of this scientific session is to shed light on the progress made in the past decade in the Radiation Oncology field.

 

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Breast, colorectal, endometrial, lung, cervical, skin, and ovarian cancers are the most common cancers in women. Knowing about these cancers and what you can do to help prevent them or detect them early (when they are small.

Breast cancer: Except for skin cancers, breast cancer is the most common cancer in women. It can happen at any age, but the risk increases with age. Some women may be more likely than others to develop breast cancer due to a variety of factors. However, every woman should be aware of the risks of breast cancer and what she can do to reduce her risk.

 

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Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy.

Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.
 

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Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin.In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin.
 

Best Cancer and oncology research conference 2025

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A biomarker is a measurable biological factor that can provide information about specific aspects of human health. Biomarkers can provide insights into each patient's individual cancer—its genetic makeup, behavior patterns, and interactions with the immune system—in the context of cancer immunotherapy.

Already, several biomarkers have been incorporated (to varying degrees) into clinical practice, while others’ value has only recently been recognized and is still being explored. Some of the most promising biomarkers today in the context of immunotherapy include:

Tumor-Associated Proteins

Pre-Existing Immune Responses

Pre-Existing Immune ResponsesPD-1/PD-L1 Expression

Tumor Mutations

The Microbiome
 

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There are many different approaches for treating cancer, depending on the type of cancer, how advanced it is, what types of treatment are available, and what the goals of treatment are.

The most common types of treatment are Surgery, Chemotherapy, Radiation Therapy, Targeted Therapy, Immunotherapy, Stem Cell or Bone Marrow Transplant, and Hormone Therapy.

This session talks about present and insights on recent advancements in various cancer treatments.
 

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Proteomics is a rapidly growing field that combines high throughput analytical methodologies such as two-dimensional gel electrophoresis and SELDI mass spectrometry methods with complex bioinformatics to study systems biology. Proteomic analyses are already widely in use for clinical studies ranging from cancer to other diseases such as cardiovascular disease, organ transplant, and pharmacodynamic studies.
 

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Drug resistance continues to be the principal limiting factor to achieving cures in patients with cancer. The problem of drug resistance in cancer has strong similarities to the field of infectious disease, in that both disciplines are challenged by highly proliferating intrinsic or extrinsic aggressors.

Combination chemotherapy thus became a new paradigm for cancer therapy that led to the development of increasingly complex regimens. In addition, a number of different approaches to dose intensity, including shorter-interval administrations of chemotherapy or higher doses of chemotherapy9\ with growth factor support to prevent continued bone marrow suppression, resulted in improved success of these therapies by preventing early regrowth of tumors.
 

Best Cancer and oncology research conference 2025

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Advances in cancer diagnostics and treatment have led to a significant increase in survival rates. With increasing knowledge and technological advancement in cancer biology, material science, and particularly, nanomedicine, providing simultaneous diagnostic and therapeutic functions for cancer. This results in a paradigm shift in focus toward long-term survivorship and quality-of-life issues.
 

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Heterogeneity within tumor cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood.
 

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The main purpose of paediatric oncology is to treat cancer and genetic tumour predisposition syndrome in infants, children's, and teenagers. Doctors in paediatric oncology are specially trained to care for children and keep them comfortable during treatment. The most common childhood cancers are lymphoma, leukaemia, neuroblastoma, bone cancer, etc. Children with cancer typically respond to better treatments, such as chemotherapy. which use strong medicine to kill cancer cells.

 

Best Cancer and oncology research conference 2025

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The type of malignancy, the location, and certain clinical problems all influence the choice of imaging modality. Each imaging technology has advantages and disadvantages. To achieve a thorough evaluation of the cancer, various imaging modalities may occasionally be combined.

SUBTOPICS:

· Uses of imaging

· X-Ray imaging

· Computed Tomography (CT) scans

· Molecular and Nuclear Imaging (PET and SPECT)

· Radiation Risk

· Cancer Biopsy & Surgical Cancer 

· Ultrasound

· Magnetic Resonance Imaging (MRI)

· Digital mammography

· Radiology

 

 

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Cancer is fundamentally a disease of tissue growth regulation. Oncogenes and tumour suppressor genes are the two primary types of impacted genes. Oncogenes are genes that promote cell growth and replication. Tumor suppressor genes are those that prevent cell division and survival. Malignant transformation can occur as a result of the emergence of novel Oncogenes, the inappropriate over-expression of known Oncogenes, or the under-expression or inactivation of Tumour Suppressor Genes.

Cancer Epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve any changes to the nucleotide sequence. Epigenetic changes are as important as genetic mutations in the transformation of normal cells to cancer cells, and their management holds remarkable promise for cancer prevention, detection, and treatment. In many kinds of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of Tumour Suppressor Genes and activation of Oncogenes by altered histone modifications, CpG island methylation patterns, and dysregulation of DNA binding proteins.

Effects of epigenetics:

Diet

Physical activity

Tobacco smoking

Alcohol consumption

Environmental pollutants

Working on night shifts

Best Cancer and oncology research conference 2025

Spectus Meetings in Barcelona, Spain

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Advanced therapies in cancer refer to innovative and cutting-edge treatments that go beyond the traditional approaches of chemotherapy, radiation therapy, and surgery. These therapies are designed to target cancer cells with greater precision, while minimizing damage to healthy cells.

Some examples of advanced therapies in cancer include:

Immunotherapy: Immunotherapy uses the body's immune system to fight cancer cells. It can involve boosting the immune system's natural response to cancer, or using drugs to target specific immune cells or molecules that are involved in cancer growth.

Targeted therapy: Targeted therapy uses drugs that specifically target the cancer cells, while leaving healthy cells alone.

Gene therapy: Gene therapy involves modifying a patient's genes to treat or prevent disease. In cancer, gene therapy can be used to modify immune cells to better recognize and attack cancer cells.

Precision medicine: Precision medicine uses advanced diagnostic techniques, such as genetic testing, to identify specific molecular characteristics of a patient's cancer. This information can be used to give treatment to the individual patient, for example by selecting a targeted therapy that is most likely to be effective based on the patient's tumor genetics.

Cancer Diagnosis is an examination which when done at the earliest, may increase the probability of the life expectancy of patients. Cancer Screening, when done on a regular basis, will help recognise the type of cancer, even before the individual experiences any signs or symptoms. The ultimate objective is to reduce or prevent the number of people who die from the disease and also to reduce the number of people who develop the disease.

The type of screening test used for cancer depends on the type of cancer being screened for. Some common screening tests for cancer include:

Mammography: a type of X-ray used to screen for breast cancer in women

Pap smear: This test is used to screen cervical cancer in women

 

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Cancer Science deals with the study on translation, clinical trials, biomarkers, cell cycle regulation, genetics, pharmacology, oncogenes, DNA damage and repair.

Cancer therapeutics include an ever-increasing array of tools that aid in the treatment of disease.

 

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Cancer is the abnormal increase in the number of cells which has the potential to invade nearby tissues or spread to other body parts which will affect the other organs too. Cancer type depends on the location of the cancer in the human body.

 

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Drug Development plays a vital role in cancer pharmacology. Many In silico methods, experimental models and target oriented approaches are being established in this field. Cancer Pharmacology generally deals with the study of anticancer agents and their experimental screening, preclinical toxicology and clinical trials, pharmacogenetics, pharmacokinetics, pharmacodynamics and drug interactions.

 

Best Cancer and oncology research conference 2025

Spectus Meetings in Barcelona, Spain

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Best Cancer and Oncology research conferences 2025 in Spain